Solid Dosage form design, namely tableting, granulation and roller compaction
Functionality of Excipients
Biopolymers as excipients, among others carrageenan, chitosan and alginate
Controlled release dosage forms
Polyelectrolyte complexes
Soft tableting: tableting of pressure sensitive materials without damage,
e.g. proteins, polymorphs, pellets with functional coatings and micro and nanoparticles
Detailed knowledge on instrumented eccentric and rotary tableting machines as well as compaction simulators
Measurement of force, time, displacement, die wall force and temperature
Advanced mathematical modeling of tableting data
Scale-Up
Molecular galenical research concerning polymorphic drugs and excipients
Spectroscopic and thermo analytical methods
Nanostuctures of solid dosage forms
Fractal analysis
Influences of relative humidity during production
Powder Technology
Quality management in formulation and development (Quality by Design and PAT according to FDA)
Spectroscopic and thermo analytical methods in the context of PAT (Process Analytical Technology)
Design of Clean rooms for sterile dosage forms
Validation
Quality Management in Pharmacy
Dangerous substances directive
Formulation and plausibility checks in semisolid dosage forms
Medication management