Picker-Freyer
 

Solid Dosage form design, namely tableting, granulation and roller compaction

Functionality of Excipients
Biopolymers as excipients, among others carrageenan, chitosan and alginate
Controlled release dosage forms
Polyelectrolyte complexes

Soft tableting: tableting of pressure sensitive materials without damage,
e.g. proteins, polymorphs, pellets with functional coatings and micro and nanoparticles

Detailed knowledge on instrumented eccentric and rotary tableting machines as well as compaction simulators
Measurement of force, time, displacement, die wall force and temperature
Advanced mathematical modeling of tableting data
Scale-Up

Molecular galenical research concerning polymorphic drugs and excipients
Spectroscopic and thermo analytical methods
Nanostuctures of solid dosage forms
Fractal analysis

Influences of relative humidity during production
Powder Technology

Quality management in formulation and development (Quality by Design and PAT according to FDA)
Spectroscopic and thermo analytical methods in the context of PAT (Process Analytical Technology)
Design of Clean rooms for sterile dosage forms
Validation

Quality Management in Pharmacy

Dangerous substances directive

Formulation and plausibility checks in semisolid dosage forms

Medication management